Hydrocortisone Medicines drm.ung. 1 x 10 g 1%

Hydrocortisone 1% Dermatological Ointment (10g Tube) – Professional Product Description

Composition & Pharmacological Properties

This topical corticosteroid preparation contains:

• Hydrocortisone acetate 1% (10mg per gram)

• Vehicle: Petroleum-based ointment for occlusive effect

As a low-potency (Group VII) glucocorticoid, it exerts:
✔ Anti-inflammatory action (inhibits phospholipase A2)
✔ Anti-pruritic effects (reduces histamine release)
✔ Vasoconstrictive properties (decreases erythema)

Therapeutic Indications

FDA/EMA-approved uses:

• Mild-to-moderate atopic dermatitis

• Contact dermatitis (allergic/irritant)

• Seborrheic dermatitis (face/scalp)

• Insect bite reactions

• Sunburn (second-line treatment)

Off-label applications:

• Mild psoriasis (non-plaque type)

• Diaper dermatitis with inflammation

Dosage & Administration

Standard protocol for adults/children ≥2 years:

1. Frequency: Apply thin layer to affected area 2-4 times daily

2. Duration:

   • Face/genitals: Max 1 week

   • Body/extremities: Max 2 weeks

3. Special populations:

   • Infants (6-24 months): Limit to 3 days

   • Elderly: Increased absorption risk

Application technique:

• Clean and dry skin before use

• Use fingertip unit (0.5g covers palm-sized area)

• Avoid mucous membranes/eyes

Safety Profile

Contraindications:
✖ Bacterial/fungal/viral skin infections
✖ Rosacea/perioral dermatitis
✖ Untreated parasitic infestations

Adverse effects (with prolonged use):

• Local: Skin atrophy, telangiectasia

• Systemic: HPA axis suppression (rare with 1%)

Drug interactions:

• Enhanced absorption with occlusive dressings

• Reduced efficacy with concomitant NSAIDs

Product Specifications

• Formulation: Non-sterile ointment

• Packaging: 10g aluminum tube

• Storage: Below 25°C (do not freeze)

• Shelf life: 3 years

Clinical Advantages

✅ Lowest-risk topical steroid for:

• Facial/Intertriginous areas

• Pediatric patients

✅ Vehicle benefits:

• Moisturizing base for dry lesions

• Better penetration than creams